Allergic Asthma (Omalizumab/Xolair, Mepolizumab/Nucala, Benralizumab/Fasenra):
Asthma triggered by allergens, causing chronic airway inflammation and constriction.
Primary Immunodeficiency (IVIG):
Weakened immune system, leading to increased susceptibility to infections.
Chronic Urticaria (Omalizumab/Xolair):
Persistent hives due to immune system dysfunction.
Hereditary Angioedema (C1 Esterase Inhibitors, Ecallantide, Icatibant):
Recurrent episodes of swelling in various body parts due to genetic deficiency.
Cardiology
Atherosclerotic Cardiovascular Disease (Alirocumab/Praluent, Evolocumab/Repatha):
Narrowing and hardening of arteries due to plaque buildup.
Congestive Heart Failure (Nesiritide/Natrecor):
Inability of the heart to pump blood effectively, leading to fluid buildup.
Pulmonary Hypertension (Epoprostenol/Flolan, Treprostinil/Remodulin, Sildenafil/Revatio):
High blood pressure in the arteries of the lungs.
Hyperlipidemia (Alirocumab/Praluent, Evolocumab/Repatha):
High levels of fats (lipids) in the blood.
Plaque Psoriasis (Adalimumab/Humira, Etanercept/Enbrel, Ustekinumab/Stelara, Secukinumab/Cosentyx):
Common form of psoriasis characterized by raised, red patches with silvery scales.
Atopic Dermatitis (Dupilumab/Dupixent):
Chronic inflammatory skin condition, also known as eczema.
Pemphigus Vulgaris (Rituximab/Rituxan):
Rare autoimmune disorder causing blistering and erosions on the skin and mucous membranes.
Hidradenitis Suppurativa (Adalimumab/Humira):
Chronic skin condition characterized by painful lumps under the skin.
Severe Acne (Isotretinoin/Accutane):
Severe form of acne resistant to other treatments, causing deep, inflamed breakouts.
Gastroenterology
Crohn’s Disease (Infliximab/Remicade, Adalimumab/Humira, Vedolizumab/Entyvio,Ustekinumab/Stelara):
Chronic inflammatory bowel disease causing inflammation in the digestive tract.
Ulcerative Colitis (Infliximab/Remicade, Adalimumab/Humira, Vedolizumab/Entyvio):
Chronic inflammatory bowel disease causing ulcers in the lining of the colon and rectum.
Short Bowel Syndrome (Teduglutide/Gattex):
Malabsorption disorder due to surgical removal of part of the small intestine.
Celiac Disease (in refractory cases) (IVIG):
Autoimmune disorder triggered by gluten intolerance, leading to damage in the small intestine.
Eosinophilic Esophagitis (Corticosteroids):
Chronic immune-mediated disorder causing inflammation in the esophagus.
Genetics
Fabry Disease (Agalsidase beta/Fabrazyme, Agalsidase alfa/Replagal):
Rare genetic disorder causing lipid buildup in cells, affecting organs and tissues.
Gaucher Disease (Imiglucerase/Cerezyme, Velaglucerase alfa/Vpriv, Taliglucerasealfa/Protalix):
Genetic disorder causing buildup of fatty substances in cells, affecting organs and tissues.
Hunter Syndrome (Idursulfase/Elaprase):
Rare genetic disorder causing buildup of certain chemicals in cells, affecting organs and tissues.
Pompe Disease (Alglucosidase alfa/Myozyme):
Genetic disorder causing buildup of glycogen in cells, affecting muscles and organs.
MPS I (Hurler Syndrome) (Laronidase/Aldurazyme):
Genetic disorder causing buildup of complex molecules, affecting multiple organs.
Spinal Muscular Atrophy (Nusinersen/Spinraza, Onasemnogene abeparvovec/Zolgensma):
Genetic disorder affecting motor neurons, leading to muscle weakness and atrophy.
Neurology
Autoimmune Encephalitis (IVIG, Rituximab/Rituxan):
Rare autoimmune condition causing inflammation of the brain.
Chronic Migraines (Erenumab/Aimovig, Fremanezumab/Ajovy, Galcanezumab/Emgality):
Recurrent headaches lasting hours to days, often accompanied by nausea and sensitivity to light and sound.
Multiple Sclerosis (Ocrelizumab/Ocrevus, Natalizumab/Tysabri, Alemtuzumab/Lemtrada):
Chronic autoimmune disease affecting the central nervous system, causing inflammation and nerve damage.
Guillain-Barré Syndrome (IVIG, Plasmapheresis):
Rare autoimmune disorder affecting the peripheral nervous system, causing muscle weakness and paralysis.
Neuromyelitis Optica (Eculizumab/Soliris, Rituximab/Rituxan):
Autoimmune disorder affecting the optic nerves and spinal cord, causing inflammation and damage.
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (IVIG, Plasmapheresis):
Autoimmune disorder affecting the peripheral nerves, causing weakness and sensory changes.
Amyotrophic Lateral Sclerosis (ALS) (Edaravone/Radicava):
Progressive neurodegenerative disease affecting nerve cells in the brain and spinal cord, causing muscle weakness and eventual paralysis.
Ophthalmology
Thyroid Eye Disease (Teprotumumab/Tepezza):
Autoimmune condition causing inflammation and swelling of the muscles and tissues around the eyes.
Wet Age-Related Macular Degeneration (Ranibizumab/Lucentis, Aflibercept/Eylea,Bevacizumab/Avastin):
Progressive eye disease affecting central vision due to abnormal blood vessel growth.
Uveitis (Adalimumab/Humira, Infliximab/Remicade):
Inflammation of the uvea, the middle layer of the eye.
Diabetic Macular Edema (Ranibizumab/Lucentis, Aflibercept/Eylea):
Swelling in the retina due to diabetes-related fluid buildup.
Retinal Vein Occlusion (Ranibizumab/Lucentis, Aflibercept/Eylea):
Blockage of veins in the retina, leading to vision loss.
Orthopedics
Osteoporosis (Zoledronic acid/Reclast, Denosumab/Prolia, Teriparatide/Forteo):
Bone disease characterized by decreased bone density and increased fracture risk.
Severe Osteoarthritis (Hyaluronic Acid Injections):
Degenerative joint disease causing joint pain and stiffness.
Paget’s Disease of Bone (Zoledronic acid/Reclast):
Chronic bone disorder causing abnormal bone growth and weakened bones.
Bone Metastases (Denosumab/Xgeva, Zoledronic acid/Reclast):
Cancer that has spread to the bones from another part of the body.
Rheumatology
Ankylosing Spondylitis (Infliximab/Remicade, Adalimumab/Humira, Secukinumab/Cosentyx):
Inflammatory arthritis affecting the spine and large joints.
Gout (Pegloticase/Krystexxa):
Inflammatory arthritis caused by uric acid crystal deposits in the joints.
Rheumatoid Arthritis (Infliximab/Remicade, Adalimumab/Humira, Tocilizumab/Actemra, Rituximab/Rituxan):
Chronic inflammatory disorder affecting joints and other tissues.
Systemic Lupus Erythematosus (SLE) (Belimumab/Benlysta, Rituximab/Rituxan):
Autoimmune disease causing inflammation and damage in multiple organs and tissues.
Psoriatic Arthritis (Infliximab/Remicade, Adalimumab/Humira, Ustekinumab/Stelara):
Inflammatory arthritis affecting people with psoriasis.
Polymyositis (IVIG):
Rare autoimmune disease causing muscle inflammation and weakness.
Vasculitis (Rituximab/Rituxan, Cyclophosphamide):
Inflammation of blood vessels, which can restrict blood flow and damage organs.
Scleroderma (Mycophenolate Mofetil/CellCept, Cyclophosphamide):
Autoimmune disease causing hardening and tightening of the skin and connective tissues.
Sjögren's Syndrome (Rituximab/Rituxan):
Autoimmune disorder affecting moisture-producing glands, leading to dry eyes and mouth.